Current Members

Our lab is committed to ensuring a safe, friendly, and accepting environment for everyone! We value the input of each and every team member and firmly believe that diversity improves the creativity and productivity of our lab. This diversity includes backgrounds of differing race, color, religion, national origin or citizenship status, gender or gender identity, pregnancy, sexual orientation, age, disability, and military status. In particular, we view the equity and inclusion of underrepresented persons as a moral obligation.

We stand opposed to racism, discrimination, and harassment of any kind. As no single statement can erase bigotry and intolerance, we recognize the importance of actions to help address these issues. We resolve to make significant efforts to improve underrepresentation and discrimination in our scientific communities.

Our lab culture is built upon mutual respect in order to maintain an environment committed to these core values. Our goal is to create a workplace where every lab member can reach their full potential!

Graduate Students

Xizheng (Colin) Diao

Bio

Xizheng started college at Sun Yet-Sen University before transferring to Hong Kong Polytechnic University where he received his B.S. degree in Chemistry in 2015. He then received his Master’s degree in Materials Science & Engineering at UF in 2017 before joining the Chemistry Ph.D. program at UF. Xizheng joined the Prentice Group in the fall of 2018.

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Julia Bonney

Bio

Julia received her B.S. degree in Chemistry from Gordon College in 2018. While there, she worked with Professor Irv Levy to create and develop greener lab procedures for the Friedel-Crafts Acylation. Julia is interested in areas of research that include not only working with instrumentation, but also exploring biomedical applications. These interests led her to pursue her Ph.D. at UF, starting in the fall of 2018 working under Professor Prentice.

Awards

  • UF Graduate Student Funding Award (GSFA) fellowship (2018-present)

Teaching Experience

  • TA- General Chemistry I Engineering Lab (UF, Fall 2018)
  • TA- Honors General Chemistry II (UF, Spring 2019)

Presentations

  • Julia Bonney and Irvin J. Levy, “Greener Friedel-Crafts Reaction Using a Deep Eutectic Solvent: An Undergraduate Laboratory Method,” American Chemical Society, New Orleans, LA, March 2018.

Publications

  • Julia R. Bonney, Boone M. Prentice, Analytical Chemistry, 2021, 93, 6311-6322. “Perspective on Emerging Mass Spectrometry Technologies for Comprehensive Lipid Structural Elucidation.”

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Jonathan Specker

Bio

Jonathan received his B.S. in Chemistry from Indiana University (IU) in 2017 with a minor in German. While at IU, he was a research assistant in Professor Mu-Hyun Baik‘s lab where he investigated mechanisms underlying organometallic catalysts for CO2 reduction using chemical simulations and density functional theory (DFT). He then became a research assistant under the supervision of Professor Megan Thielges where he studied the structure of proteins expressed with non-native amino acid vibrational probes using FTIR spectroscopy. Following graduation, he served as a laboratory technician in the Thielges lab from 2017-2018 where he worked on cyano-labeled cyctochrome P450 variant protein expression and purification.

Jonathan joined the Prentice Group in the fall of 2018, where he now works on fundamental charge inversion ion activation strategies using next-generation mass spectrometry instrumentation. This work is focused on using fundamental charge inversion ion/ion chemistries to enable the enhanced structural identification phospholipids in imaging mass spectrometry (IMS). In addition, he is working in collaboration with Dr. Joseph Zackular (University of Pennsylvania, Children’s Hospital of Pennsylvania) to study the metabolic interactions of Clostridium difficile during co-infection with other gut microbiota in the gastrointestinal tract. This application utilizes high resolution accurate mass (HRAM) imaging mass spectrometry to identify biomolecules of interest and elucidate biochemical mechanisms during Clostridium difficile infection.

Awards

  • Charles and Monica Burkett Family Summer Fellowship (UF, 2021)
  • Graduate Student Teaching Award (UF, 2020)
  • Grinter Research Fellowship (UF, 2018)
  • Robert & Marjorie Mann Summer Research Grant (IU, 2016)

Publications

  • Jonathan T. Specker, Steven L. Van Orden, Mark E. Ridgeway, Boone M. Prentice, Analytical Chemistry2020, 92, 13192-13201. “Identification of phosphatidylcholine isomers in imaging mass spectrometry using gas-phase charge inversion ion/ion reactions”
  • Sashary Ramos, Amanda L. Le Sueur, Rachel H. Horness, Jonathan T. Specker, Jessica A. Collins, Katherine E. Thibodeau, Megan C. Thielges, The Journal of Physical Chemistry B, 2019, 123(9), 2114-2122. “Heterogeneous and highly dynamic interface in plastocyanin–cytochrome f complex revealed by site-specific 2D–IR spectroscopy”

Presentations

  • Jonathan T. Specker*, Boone M. Prentice, “Gas-phase separation and concentration of phosphatidylcholine lipids using charge inversion ion/ion reactions enabled on a FT-ICR mass spectrometer,” Oral presentation, ID–301075, June 1, 2020, Proceedings of the 68th ASMS Conference on Mass Spectrometry and Allied Topics, Online Meeting, June 1-12, 2020.
  • Jonathan T. Specker*, Steven L. Van Orden, Boone M. Prentice, “Identification of phosphatidylcholine lipids in imaging mass spectrometry using gas-phase charge inversion ion/ion reactions enabled on a FT-ICR mass spectrometer,” Oral presentation, ID–299803, June 3, 2019, Proceedings of the 67th ASMS Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, June 2-6, 2019.

Teaching Experience

  • TA- CHM2051 – General Chemistry II Honors (UF, 2020)
  • TA- CHM 4130 – Instrumental Analysis (UF, 2019-2020)
  • TA- CHM3120L Analytical Chemistry Lab (UF, 2018-2020)

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Yuzhuo (Gina) Ji

Bio

Gina received her B.S. in Resource Science and Development of Traditional Chinese Medicine from China Pharmaceutical University followed by her M.S. in Medicinal Chemistry from Peking University. Gina joined the Prentice Group in the fall of 2019.

Publications

  • Yuzhuo Ji, Jiali Yang, Li Wu, Lijia Yu, and Xinjing Tang, “Photochemical regulation of gene expression using caged siRNAs with single terminal vitamin E modification.” Angewandte Chemie International Edition 2016, 55, 2152-2156.
  • Jiali Yang, Lijia Yu, Liangliang Zhang, Xingsu Long, Yuzhuo Ji, and Xinjing Tang, “Synthesis and Evaluation of Caged siRNA with Terminal Single Vitamin E Modification.” Current Protocols in Nucleic Acid Chemistry 2016, 67, 16-6.
  • Wengang Ji, Yuzhuo Ji, Qingqing Jin, Qingxiao Tong, and Xinjing Tang, “Heavy atom quenched coumarin probes for sensitive and selective detection of biothiols in living cells.” Analyst 2015, 140, 4379-4383.
  • Long Li, Yuzhuo Ji, and Xinjing Tang, “Quaternary ammonium promoted ultra-selective and sensitive fluorescence detection of fluoride ion in water and living cells.” Analytical Chemistry 2014, 86, 10006-10009.
  • Peng Wang, Yuzhuo Ji, Zhixuan Wang, Xinjing Tang, “Supramolecular self-assembly for delivery of oligonucleotides and its phototriggered unpacking in living cells.” Journal of Chinese Pharmaceutical Sciences 2014, 23, 454–462.

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Woo-Young Kang

Bio

Woo-Young received his B.S. degree in Applied Chemistry from Sejong University in Korea and his M.S. in Chemistry from Sejong University in Korea. He then served as a research scientist in the Chemical Analysis Center at the Korea Research Institute of Chemical Technology in Daejeon, Korea under the advisement of Dr. Jonghyuk Kim from 2011-2012.  After stops at the University of Louisville (Louisville, KY) and BioSpectrum, Inc. (Gyeonggi-do, Korea), he became a research scholar in the resource center for stable isotope-resolved metabolomics (RC-SIRM) at the Markey Cancer Center at the University of Kentucky under the direction of Prof. Richard M. Higashi from 2016-2019.  Woo-Young joined the Prentice Group in the fall of 2019.

Awards

  • UF Graduate Student Funding Award (GSFA) fellowship (2019-present)
  • University Fellowship (University of Louisville, 2013)
  • Dean’s Honor Scholarships (Sejong University, 2007-2008)
  • Honors Scholarships (Sejong University, 2002-2003)

Publications

  • Yuntong Li, Teresa W.M. Fan, Andrew N. Lane, Woo-Young Kang, Susanne M. Arnold, Arnold J. Stromberg, Chi Wang and Li Chen, “SDA: a semi-parametric differential abundance analysis method for metabolomics and proteomics data.” BMC Bioinformatics 2019, 20, 501.
  • Woo-Young Kang, Patrick T. Thompson, Salim S. El-Amouri, Teresa W.M. Fan, Andrew N. Lane, Richard M. Higashi, “Improved segmented-scan spectral stitching for stable isotope resolved metabolomics (SIRM) by ultra-high-resolution Fourier transform mass spectrometry.” Analytica Chimica Acta 2019, 1080, 104-115.
  • Teresa W.M. Fan, Xiaofei Zhang, Chi Wang, Ye Yang, Woo-Young Kang, Susanne Arnold, Richard M. Higashi, Jinze Liu, Andrew N. Lane, “Exosomal Lipids for Classifying Early and Late Stage Non-Small Cell Lung Cancer.” Analytica Chimica Acta 2018, 1037, 256-264.
  • Woo Young Kang, Seol Hyun Kim, Young Kee Chae, “Stress Adaptation of Saccharomyces cerevisiae as Monitored via Metabolites by Using Two Dimensional NMR Spectroscopy.” FEMS Yeast Research  2012, 12, 608-616.
  • Young Kee Chae, Woo Young Kang, Joong-Hee Jang, Sung-Seen Choi, “A Simple NMR Method to Measure Crosslink Density of Natural Rubber Composite.” Polymer Testing 2010, 29, 953-957.
  • Woo-Young Kang, Young Kee Chae, “Stationary phase expression, purification, and characterization of XorKI, a restriction endonuclease from Xanthomonas oryzae pv. Oryzae.” Protein & Peptide Letters 2010, 17, 381-385.
  • Young Kee Chae, Woo-Young Kang, Seong Hwan Kim, Jong Eun Joo, Joon Kil Han, Boo Whan Hong, “Combining Information of Common Metabolites Reveals Global Differences between Colorectal Cancerous and Normal Tissues.” Bulletin of the Korean Chemical Society 2010, 31, 379-383.

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Julie Liang

Bio

Julie received her B.S. in Chemistry with honors from New York University Shanghai in 2019. During her time at NYU Shanghai, she conducted research in Professor John Zhang’s lab investigating computational drug screening. She also interned at Nanjing Agile, a biotech company developing heparin electrochemical sensors. Julie joined the Prentice group in fall 2019.

Awards

  • UF Grinter Fellowship (2019)

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Chelsey Mertens

Bio

Chelsey received her B.S. in Psychology in 2013 and her B.S. in Biochemistry in 2018, both from the University of Tennessee at Chattanooga (UTC).  While a psychology undergraduate, she studied olfactory senses of end stage renal failure patients in collaboration with the Chemistry Department.  When Chelsey returned to obtain a BS in Biochemistry, she studied pyrimidine degradative pathways in Pseudomonas syringae.  After joining the Prentice Lab in fall of 2019, Chelsey began work on identifying Tricarboxylic Acid Cycle metabolites and cardiolipins in septic hearts using mass spectrometry imaging.  She also studies elucidating the MALDI plume environment using short peptides and photo-cleavable species.

Awards

  • Outstanding Teaching Assistant (UTC, 2018)
  • Westbrook Research Scholar (UTC, 2018)
  • Clarence T. Jones Observatory Service Award (UTC, 2018)
  • Marvin L. Anthony Service Award (UTC, 2018-2019)

Teaching Experience

  • TA- General Chemistry Lab (UF, 2019-2020)
  • TA- Analytical Chemistry Lab (UF, 2020-2021)
  • TA- General Chemistry Lab (UTC, 2016-2018)
  • TA- Quantitative Analysis Lab (UTC, 2017-2018)
  • TA- Organic Chemistry Lab (UTC, 2017-2018)
  • TA- Physical Chemistry Lab (UTC, 2018)

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Tingting Yan

Bio

Tingting graduated from Beijing University of Chemical Technology (BUCT) with a B.S. degree in Chemistry in 2015. She then received her M.S. degree in Chemical Engineering and Technology at BUCT in 2018. Her previous research focused on the synthesis of nanomaterials for applications in catalysis. Currently, she is interested in mass spectrometry, which drew her to the Prentice group in fall 2019.

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Justin Ellenburg

Bio

Justin received his B.S. in Biology in 2018 from the University of North Georgia (UNG). During his time there he worked on method development for a liquid chromatographic separation of Oakworm extracts under the direction of Dr. Paula Nolibos. After graduating he worked for UNG’s chemistry department, while rounding out his undergraduate chemistry coursework. He joined the Prentice group in fall 2020.

Awards

  • UF Graduate Student Funding Award (GSFA) fellowship (2020-present)

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David Donndelinger

Bio

After receiving his B.S. in Chemistry in 2013 from the University of Illinois, David commissioned into the US Air Force. For three and a half years, he worked at the the Air Force Technical Applications Center as a satellite data analyst and radiochemist.  In 2018, David completed his MS in Chemistry at the Georgia Institute of Technology where he performed mass spectrometry research under the guidance of Dr. Facundo Fernandez.  He was then assigned to the Air Force Research Lab in Ohio studying human performance aiming to restore, sustain, and enable military members throughout the Department of Defense.  David joined the Prentice group in the summer of 2021 and hopes to apply analytical chemistry and mass spectrometry fundamentals to the challenges our military members face.

Awards

  • Lance P. Sijan Leadership Award – Junior Officer Category (2020)
  • James W. Brinkley Leadership Award (2020)

Publications

  • Donndelinger, D. V. “Rapid characterization of poor-quality medicines using mass spectrometry.” Masters dissertation, Georgia Institute of Technology. 2018.
  • Zambrzycki, S. C., Caillet, C., Vickers, S., Bouza, M., Donndelinger, D. V., Winalski, L. C., Bernier, M. C., Grigger, W. R., Newton, P. N., & Fernández, F. M.”Evaluation of 12 portable devices for quality screening of medicines”.Manuscript submitted for publication. School of Chemistry and Biochemistry, Georgia Institute of Technology. 2021.

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Yingchan Guo

Bio

Yingchan completed her B.S. in Chemistry at the Beijing University of Chemical Technology, Beijing, China in 2020. Her research there involved the study of immobilized double enzyme based DNA nanotechnology and fuctionalized magnetic spheres. During the summer of 2019, she conducted research modeling Vesicular Stomatitis Virus (VSV) infection looking into the innate immune response and a viral antagonism strategy. She joined the Prentice lab in the fall of 2021.

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Michael Christopher

Bio

Michael received his B.S. in Biochemistry from North Carolina State University in 2021. At NCSU, he was part of the Dr. Erin Baker Lab where he conducted research in plant metabolic engineering as well as in ion mobility-mass spectrometry of lipids. He also had the opportunity to discover his passion for metabolomics while interning at Lawrence Berkeley National Lab (“Berkeley Lab”) for a semester during his undergraduate degree. Michael joined the Prentice group in collaboration with the Garrett group in fall of 2021.

Awards

  • Grinter Fellowship Award – University of Florida Department of Chemistry (2020)

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Troy Scoggins

Bio

Troy comes to the Florida from North Carolina where he earned his B.S. in Chemistry at the University of North Carolina at Chapel Hill in 2020. While at UNC, he conducted research improving tendon healing through desferrioxamine coated sutures under Dr. Paul Weinhold. After college, he was an Associate Scientist at Tergus Pharma for a year under the In Vitro Release Testing Department developing methods for IVRT analysis of topical pharmaceutical products. Troy joined the Prentice lab in the fall of 2021 working on novel mass spectrometry instrumentation and imaging mass spectrometry of biological samples.

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Ariana Stratton

Bio

Ariana earned her B.S. in Chemistry from the University of Central Florida in 2021. While at UCF, she conducted research under Dr. Andres Campiglia analyzing polycyclic aromatic hydrocarbons (PAHs) found in cigarettes and smoke using absorbance, fluorescence, and laser spectroscopy. She joined the Prentice lab in the fall of 2021.

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Undergraduate Students

Nicholas Ellin

Bio

Nick is an fourth-year undergraduate pre-medical student majoring in Biochemistry. During a physician shadowing experience with a pediatric orthopedic surgeon, he learned the proper techniques for reading X-rays and MRIs, piquing his interest in biomedical imaging. Nick is particularly interested in the biomedical applications of imaging mass spectrometry.

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Alyssa Moore

Bio

Alyssa is a fourth-year undergraduate student majoring in Chemistry. She received her Associate of Arts Degree from Florida State College at Jacksonville in 2018 before moving to Gainesville to pursue her Bachelor’s Degree at UF. Alyssa joined the Prentice Lab in spring 2020 and is interested in the biomedical applications of imaging mass spectrometry..

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Yu Tin Lin

Bio

Yu Tin is a second-year undergraduate pre-medical student majoring in Biochemistry. He enrolled at UF in the fall of 2020 and became interested in imaging mass spectrometry when his General Chemistry TA showed him the technology. Yu Tin joined the Prentice Group in the spring of 2020.

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Clara Summerford

Bio

Clara is a second-year undergraduate mechanical engineering major who is also interested in materials engineering and biomedical applications. She joined the Prentice Group in the summer of 2021 and will focus on instrument design and the intersections between engineering and analytical chemistry.

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