In this age of molecular science, mass spectrometry offers enormous potential for biological discovery by both comprehensively testing and generating hypotheses. However, improvements in sensitivity, molecular specificity, and spatial resolution are crucial in order to answer increasingly complicated biological questions. Our lab focuses on the development of gas-phase ion/ion, ion/molecule, ion/photon, and ion/electron interactions to improve analytical performance. These gas-phase transformations are fast, efficient, and specific, making them ideal reactions for implementation in imaging mass spectrometry experiments.
Current Funding: NIH NIGMS R01 (GM138660)